SCHEMBL996479

SCHEMBL996479

CC(=O)c1ccc2c(c1)C(C)(C)C(C)(C)C2(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
HSD17B1 P14061 2/20 0.43
PDK2 Q15119 1/20 0.41
CYP2A6 P11509 1/20 0.40
RXRA P19793 2/20 0.39
RXRB P28702 2/20 0.39
PKM P14618 1/20 0.39
MAPK1 P28482 1/20 0.38
HPGD P15428 3/20 0.38
ALDH1A1 P00352 2/20 0.38
PRKCI P41743 1/20 0.38
S100A4 P26447 1/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RARB P10826 1/20 0.38
RARG P13631 1/20 0.38
RXRG P48443 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15040997 0.78 MAPT (0.57) MAPTRAB9ANPC1HSD17B1PDK2
SCHEMBL8985618 0.77 MAPT (0.47) MAPTRAB9ANPC1HSD17B1PDK2
SCHEMBL8995963 0.76 MAPK1 (0.38) MAPTRAB9ANPC1PDK2MAPK1
SCHEMBL20838212 0.75 RXRA (0.66) RXRARXRBKMT2ARARBRARG
SCHEMBL9116780 0.75 MAPT (0.50) MAPTRAB9ANPC1HSD17B1PDK2
SCHEMBL19075863 0.74 PDK2 (0.51) MAPTRAB9ANPC1HSD17B1PDK2
SCHEMBL4422379 0.74 RXRA (0.53) MAPTRAB9ANPC1RXRARXRB
SCHEMBL14008397 0.74 MAPT (0.44) MAPTRAB9ANPC1HSD17B1PDK2
SCHEMBL2195224 0.74 RXRA (0.66) RAB9ANPC1RXRARXRBMAPK1
SCHEMBL15040998 0.73 MAPT (0.57) MAPTRAB9ANPC1HSD17B1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114514251-B Polymer dispersions and fabric conditioning compositions comprising the same 罗地亚经营管理公司 2024-06-14 CN disclosed
CN-117897132-A Personal care compositions containing metablend for rebalancing skin microbiome 高露洁-棕榄公司 2024-04-16 CN disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
EP-3746420-A1 ENOL ETHER PROPERFUME Firmenich SA (CH) 2020-12-09 EP disclosed
CN-110959024-A Detergent composition containing perfume 罗地亚经营管理公司 2020-04-03 CN disclosed
WO-2019243501-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2019-12-26 WO disclosed
CN-105585601-B Anti-aging skin external composition and preparation method thereof 株式会社林原 2018-11-13 CN disclosed
CN-105585601-A Anti-aging skin external composition and preparation method thereof HAYASHIBARA CO 2016-05-18 CN disclosed
CN-104918603-A Anti-aging skin external composition and preparation method thereof HAYASHIBARA CO 2015-09-16 CN disclosed
EP-2020225-B1 Fragrance composition KAO CORP (JP) 2014-10-08 EP disclosed
US-6562771-B2 Perfumes UNILEVER HOME & PERSONAL CARE USA, A DIVISION OF CONOPCO, INC. 2003-05-13 US disclosed
US-20010036907-A1 Laundry treatment for fabrics UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2001-11-01 US disclosed
WO-1995019948-A1 NOVEL ALKYL TETRALIN ALDEHYDE COMPOUNDS UNION CAMP CORPORATION (US) 1995-07-27 WO disclosed
WO-1995019761-A1 NOVEL ALKYL INDANE ALDEHYDE COMPOUNDS UNION CAMP CORPORATION (US) 1995-07-27 WO disclosed
US-5403823-A Fragrant musk-like aroma UNION CAMP CORPORATION (US) 1995-04-04 US disclosed
US-5401720-A Musk perfume UNION CAMP CORPORATION (US) 1995-03-28 US disclosed
WO-1995000113-A1 NOVEL FORMATE ESTER INDANE COMPOUNDS UNION CAMP CORPORATION (US) 1995-01-05 WO disclosed
WO-1995000114-A1 TETRALINE® FORMATE ESTER AROMA CHEMICALS UNION CAMP CORPORATION (US) 1995-01-05 WO disclosed
US-5292719-A Perfumes, colognes, soaps and cosmetics; musk aroma UNION CAMP CORPORATION (US) 1994-03-08 US disclosed
US-5292720-A Formate ester indane compounds UNION CAMP CORPORATION (US) 1994-03-08 US disclosed