Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.34 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1243818 | 0.87 | CYP19A1 (0.49) | CYP19A1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL9965186 | 0.86 | CYP19A1 (0.43) | CYP19A1MEN1PSIP1AXLMKNK1 | |
| SCHEMBL9965132 | 0.86 | KCNA5 (0.40) | CYP19A1MEN1PSIP1AXLMKNK1 | |
| SCHEMBL1242145 | 0.83 | CYP19A1 (0.45) | CYP19A1CYP17A1KCNA5CYP11B1 | |
| SCHEMBL1242629 | 0.77 | CYP19A1 (0.57) | CYP19A1CYP17A1KCNA5CYP11B1 | |
| SCHEMBL1243320 | 0.76 | CYP19A1 (0.44) | CYP19A1SMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL17064640 | 0.74 | SMN1; SMN2 (0.65) | CYP19A1MEN1PSIP1AXLMKNK1 | |
| SCHEMBL12890821 | 0.71 | KCNA5 (0.36) | CYP19A1KCNA5 | |
| SCHEMBL1242323 | 0.71 | CYP19A1 (0.39) | CYP19A1KCNA5KDM4E | |
| SCHEMBL1242375 | 0.70 | CFTR (0.41) | CYP19A1SMN1; SMN2CFTRSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082746-A2 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2012-06-21 | — | — | WO | disclosed |