⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854399 | 0.75 | — | — | |
| SCHEMBL822928 | 0.75 | — | — | |
| SCHEMBL9961903 | 0.69 | — | — | |
| SCHEMBL25343386 | 0.65 | — | — | |
| SCHEMBL5172041 | 0.65 | — | — | |
| SCHEMBL14272678 | 0.61 | — | — | |
| SCHEMBL11024745 | 0.61 | — | — | |
| SCHEMBL14500145 | 0.61 | — | — | |
| Benzene SCHEMBL9421890 | 0.59 | ALDH1A1 (0.32) | — | |
| SCHEMBL8629 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8582192-B2 | Polarizing photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-8545984-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8518546-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-8236716-B2 | Photochromic benzopyrano-benzopyrans with further fusing | RODENSTOCK GMBH (DE) | 2012-08-07 | — | — | US | disclosed |
| US-20120157677-A1 | LACTONE COMPOUNDS AND MATERIALS MADE THEREFROM | TRANSITIONS OPTICAL INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120156508-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120157696-A1 | METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120156521-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20110279883-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110201489-A1 | PHOTOCHROMIC BENZOPYRANO-BENZOPYRANS WITH FURTHER FUSING | RODENSTOCK GMBH (DE) | 2011-08-18 | — | — | US | disclosed |
| US-20070098968-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-05-03 | — | — | US | disclosed |
| US-20070075388-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-04-05 | — | — | US | disclosed |
| US-20070053047-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-20070053050-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-20070053049-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-20070053048-A1 | Polirizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-20070047055-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-01 | — | — | US | disclosed |
| US-20070047054-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-01 | — | — | US | disclosed |
| US-20070047053-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-01 | — | — | US | disclosed |
| US-20070041073-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-02-22 | — | — | US | disclosed |