Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 6/20 | 1.00 |
| ▸ | FOLH1 | Q04609 | 14/20 | 0.75 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316981 | 1.00 | NAALAD2 (1.00) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL13515316 | 1.00 | NAALAD2 (1.00) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL11936654 | 0.88 | NAALAD2 (1.00) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL11936623 | 0.88 | NAALAD2 (1.00) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL13538922 | 0.88 | NAALAD2 (0.78) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL31294302 | 0.87 | NAALAD2 (0.77) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL11936645 | 0.87 | FOLH1 (0.78) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL4317844 | 0.87 | NAALAD2 (0.77) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL11936648 | 0.87 | NAALAD2 (0.77) | NAALAD2FOLH1RIMKLA | |
| SCHEMBL11977627 | 0.87 | NAALAD2 (0.77) | NAALAD2FOLH1RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200093827-A1 | Pemetrexed Polymeric Nanoparticles And Methods Of Making And Using Same | PFIZER INC. (US) | 2020-03-26 | — | — | US | disclosed |
| WO-2012082903-A2 | TREATMENT OF COGNITIVE IMPAIRMENT IN A SUBJECT WITH A NEUROLOGICAL AUTOIMMUNE DISEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200093827-A1 | Pemetrexed Polymeric Nanoparticles And Methods Of Making And Using Same | MTHFD1, TYMP, FPGS | NAALAD2 3323/4885FOLH1 51/4885RIMKLA 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.