Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.72 |
| ▸ | NAALAD2 | Q9Y3Q0 | 6/20 | 0.72 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16580430 | 1.00 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLALMNAMAPK1 | |
| SCHEMBL11936626 | 1.00 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLALMNAMAPK1 | |
| SCHEMBL14331633 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL11936652 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL22636039 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL11936625 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL4139212 | 0.91 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLALMNAMAPK1 | |
| SCHEMBL16580110 | 0.91 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLALMNAMAPK1 | |
| SCHEMBL11936627 | 0.91 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLALMNAMAPK1 | |
| SCHEMBL26090455 | 0.91 | LMNA (0.66) | FOLH1NAALAD2RIMKLALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082903-A2 | TREATMENT OF COGNITIVE IMPAIRMENT IN A SUBJECT WITH A NEUROLOGICAL AUTOIMMUNE DISEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-06-21 | — | — | WO | disclosed |