Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965413 | 0.91 | CNR1 (0.46) | POLBL3MBTL1CNR1CNR2NAMPT | |
| SCHEMBL9965447 | 0.85 | POLB (0.48) | POLBL3MBTL1CNR1CNR2NAMPT | |
| SCHEMBL9965382 | 0.78 | PTPN1 (0.51) | POLBL3MBTL1ALDH1A1TSHRKMT2A | |
| SCHEMBL9965376 | 0.78 | SMN1; SMN2 (0.50) | CYP2C9CYP2C19LMNAALDH1A1TSHR | |
| SCHEMBL642098 | 0.76 | NPSR1 (0.52) | CNR1CNR2LMNAALDH1A1KMT2A | |
| SCHEMBL642620 | 0.76 | CNR1 (0.52) | L3MBTL1CNR1CNR2ALDH1A1KMT2A | |
| SCHEMBL5073514 | 0.75 | CHRM1 (0.46) | KDM4ECYP2C9LMNAALDH1A1KMT2A | |
| SCHEMBL9965470 | 0.73 | NPSR1 (0.49) | L3MBTL1LMNAALDH1A1TSHRKMT2A | |
| SCHEMBL10173916 | 0.73 | P2RX7 (0.42) | L3MBTL1KDM4ELMNAALDH1A1TSHR | |
| SCHEMBL641134 | 0.73 | CNR1 (0.49) | CNR1CNR2LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960347-B1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | STERIX LTD (GB) | 2012-06-20 | — | — | EP | disclosed |