SCHEMBL9966129

SCHEMBL9966129

COC(=O)c1ccc(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)S(=O)(=O)NS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.50
RAB9A P51151 2/20 0.48
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPT P10636 3/20 0.40
HPGD P15428 2/20 0.40
EGFR P00533 1/20 0.38
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
CA14 Q9ULX7 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA7 P43166 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12399049 0.88 STS (0.47) STSRAB9ACA1CA2SMN1; SMN2
SCHEMBL13183465 0.87 KMT2A (0.39) STSRAB9ACA1CA2ALDH1A1
SCHEMBL26452047 0.85 CXCR2 (0.36) STSCA1CA2SMN1; SMN2MAPT
SCHEMBL9966140 0.84 STS (0.55) STSRAB9ACA1CA2LMNA
SCHEMBL13183470 0.82 CA1 (0.41) CA1CA2SMN1; SMN2CA9
SCHEMBL19558182 0.82 PTGS1 (0.40) STSRAB9ACA1CA2HPGD
SCHEMBL18499595 0.81 STS (0.39) STSRAB9ACA1CA2LMNA
SCHEMBL15450680 0.81 STS (0.36) STSRAB9ACA1CA2SMN1; SMN2
SCHEMBL2740703 0.81 STS (0.41) STSRAB9ACA1CA2LMNA
SCHEMBL17953183 0.81 STS (0.41) STSCA1CA2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120156618-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed