Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594300 | 0.86 | ALDH1A1 (0.58) | ALDH1A1GAAPOLBL3MBTL1PTGES2 | |
| SCHEMBL1595349 | 0.86 | ALDH1A1 (0.60) | ALDH1A1GAAPOLBL3MBTL1PTGES2 | |
| SCHEMBL1594739 | 0.85 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBL3MBTL1PTGES2 | |
| SCHEMBL1593690 | 0.83 | ALDH1A1 (0.65) | ALDH1A1GAAPOLBL3MBTL1PTGES2 | |
| SCHEMBL1594515 | 0.83 | ALDH1A1 (0.65) | ALDH1A1GAAPOLBL3MBTL1PTGES2 | |
| SCHEMBL1593789 | 0.82 | ALDH1A1 (0.64) | ALDH1A1GAAPOLBL3MBTL1RAB9A | |
| SCHEMBL1594752 | 0.82 | ALDH1A1 (0.64) | ALDH1A1GAAPOLBL3MBTL1RAB9A | |
| SCHEMBL1594712 | 0.82 | ALDH1A1 (0.64) | ALDH1A1GAAPOLBL3MBTL1RAB9A | |
| SCHEMBL1594579 | 0.82 | ALDH1A1 (0.64) | ALDH1A1GAAPOLBL3MBTL1PTGES2 | |
| SCHEMBL1595135 | 0.82 | ALDH1A1 (0.56) | ALDH1A1GAAPOLBL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465850-A1 | THERAPEUTIC COMPOUNDS | Helicon Therapeutics, Inc. (US) | 2012-06-20 | — | — | EP | disclosed |
| WO-2007100851-A1 | THERAPEUTIC COMPOUNDS | HELICON THERAPEUTICS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |