Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.47 |
| ▸ | TUBB | P07437 | 4/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996627 | 1.00 | TUBB1 (0.52) | TUBB1ABCG2HPGDMEN1KMT2A | |
| SCHEMBL997849 | 0.96 | TUBB1 (0.52) | TUBB1ABCG2HPGDMEN1KMT2A | |
| SCHEMBL997847 | 0.96 | TUBB1 (0.52) | TUBB1ABCG2HPGDMEN1KMT2A | |
| SCHEMBL997037 | 0.86 | TUBB1 (0.54) | TUBB1ABCG2HPGDMEN1KMT2A | |
| SCHEMBL997041 | 0.86 | TUBB1 (0.54) | TUBB1ABCG2HPGDMEN1KMT2A | |
| SCHEMBL997145 | 0.85 | TUBB1 (0.53) | TUBB1ABCG2HPGDMEN1KMT2A | |
| SCHEMBL997144 | 0.85 | TUBB1 (0.53) | TUBB1ABCG2HPGDMEN1KMT2A | |
| SCHEMBL997005 | 0.84 | TUBB4A (0.59) | TUBB1ABCG2MEN1KMT2ALMNA | |
| SCHEMBL997004 | 0.84 | TUBB4A (0.59) | TUBB1ABCG2MEN1KMT2ALMNA | |
| SCHEMBL997937 | 0.78 | TUBB1 (0.62) | TUBB1ABCG2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |