Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940254 | 0.97 | LTA4H (0.57) | LTA4HCNR1CNR2DRD1DRD4 | |
| SCHEMBL9967009 | 0.94 | LTA4H (0.58) | LTA4HCNR1CNR2DRD1DRD4 | |
| SCHEMBL9966735 | 0.91 | LTA4H (0.54) | LTA4HESR1ESR2OPRK1PSMB1 | |
| SCHEMBL9966732 | 0.90 | LTA4H (0.55) | LTA4HESR1ESR2OPRK1PSMB1 | |
| SCHEMBL9966789 | 0.90 | LTA4H (0.55) | LTA4HESR1ESR2OPRK1PSMB1 | |
| SCHEMBL9966793 | 0.89 | LTA4H (0.56) | LTA4HNPC1RAB9AESR1ESRRG | |
| SCHEMBL9966961 | 0.88 | LTA4H (0.55) | LTA4HESR1ESR2OPRK1PSMB1 | |
| SCHEMBL9966977 | 0.88 | ESR1 (0.58) | LTA4HESR1ESRRGESR2 | |
| SCHEMBL9940306 | 0.87 | LTA4H (0.56) | LTA4HESR1ESR2OPRK1PSMB1 | |
| SCHEMBL9940088 | 0.87 | LTA4H (0.56) | LTA4HESR1ESR2OPRK1PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |