Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966792 | 0.90 | ESR1 (0.74) | ESR1ESR2F2 | |
| SCHEMBL9966808 | 0.89 | ESR1 (0.76) | ESR1ESR2LTA4HF2 | |
| SCHEMBL9966810 | 0.89 | ESR1 (0.76) | ESR1ESR2LTA4HF2 | |
| SCHEMBL9966807 | 0.88 | ESR1 (0.63) | ESR1ESR2LTA4HF2 | |
| SCHEMBL13897617 | 0.88 | ESR1 (0.81) | ESR1ESR2LTA4HF2 | |
| SCHEMBL9935250 | 0.87 | LTA4H (0.63) | ESR1ESR2LTA4HCA12CA1 | |
| SCHEMBL9966889 | 0.87 | ESR1 (0.62) | ESR1ESR2LTA4HF2 | |
| SCHEMBL9966989 | 0.86 | ESR1 (0.59) | ESR1ESR2LTA4HF2 | |
| SCHEMBL9966806 | 0.86 | ESR1 (0.60) | ESR1ESR2F2 | |
| SCHEMBL9966977 | 0.86 | ESR1 (0.58) | ESR1ESR2LTA4HF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |