⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366321 | 0.97 | — | — | |
| SCHEMBL8326504 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL995557 | 0.97 | DNM1 (0.50) | — | |
| SCHEMBL1403811 | 0.97 | — | — | |
| SCHEMBL3098989 | 0.90 | — | — | |
| SCHEMBL84155 | 0.82 | — | — | |
| SCHEMBL9668013 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL7870810 | 0.78 | — | — | |
| SCHEMBL9421489 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL9670647 | 0.78 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980003-A | Fatty acid conjugates of nucleic acids | 嘉德治疗有限责任公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-111971269-B | Reaction of glycolaldehyde | 塔明克私人有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117487811-A | Compositions and methods for treating complications and diseases associated with von willebrand factor | 邦德治疗有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20240002861-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF BLEEDING DISORDERS | BAND THERAPEUTICS, LLC (US) | 2024-01-04 | — | — | US | disclosed |
| CN-110520128-B | Compositions and methods for treating complications and diseases associated with von Willebrand Factor | 邦德治疗有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-116723863-A | Compositions and methods for treating hemorrhagic disorders | 邦德治疗有限公司 | 2023-09-08 | — | — | CN | disclosed |
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| CN-106257335-B | Electrophotographic member, process cartridge, and electrophotographic apparatus | 佳能株式会社 | 2020-01-24 | — | — | CN | disclosed |
| CN-110023499-A | Tumor necrosis factor-alpha (TNF-α) combines aptamers and its therapeutical uses | 拜欧亿思有限公司 | 2019-07-16 | — | — | CN | disclosed |
| WO-2018145086-A1 | MULTIMERIC OLIGONUCLEOTIDES HAVING DECREASED KIDNEY CLEARANCE | MPEG LA, LLC (US) | 2018-08-09 | — | — | WO | disclosed |
| WO-1999005319-A2 | METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY | RAPIGENE, INC. (US) | 1999-02-04 | — | — | WO | disclosed |
| CN-1147267-A | Polymerizable composition and application thereof | CIBA GEIGY AG (CH) | 1997-04-09 | — | — | CN | disclosed |
| US-5470834-A | Metalloproteinase enzyme inhibitors for arthritis, rheumatism and cancers | FLORIDA STATE UNIVERSITY (US) | 1995-11-28 | — | — | US | disclosed |
| WO-1994013325-A9 | PEPTIDE LINKERS FOR IMPROVED OLIGONUCLEOTIDE DELIVERY | — | 1994-08-18 | — | — | WO | disclosed |
| WO-1994013325-A2 | PEPTIDE LINKERS FOR IMPROVED OLIGONUCLEOTIDE DELIVERY | MICROPROBE CORPORATION (US) | 1994-06-23 | — | — | WO | disclosed |
| EP-0562832-A1 | Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0431080-A4 | COMPOSITIONS AND METHODS FOR DRUG DELIVERY AND CHROMATOGRAPHY | — | 1992-10-21 | — | — | EP | disclosed |
| EP-0431080-A1 | COMPOSITIONS AND METHODS FOR DRUG DELIVERY AND CHROMATOGRAPHY | AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED (AU) | 1991-06-12 | — | — | EP | disclosed |
| WO-1990002141-A1 | COMPOSITIONS AND METHODS FOR DRUG DELIVERY AND CHROMATOGRAPHY | AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED (AU) | 1990-03-08 | — | — | WO | disclosed |
| US-4206117-A | Pyridinyl aminoalkyl ethers | BASF AKTIENGESELLSCHAFT (DE) | 1980-06-03 | — | — | US | disclosed |