Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 8/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9940104 | 0.99 | KDM4E (0.47) | KDM4ELTA4HHRH3OPRK1SIGMAR1 | |
| SCHEMBL9966992 | 0.91 | LTA4H (0.52) | KDM4ELTA4HHRH3OPRK1 | |
| SCHEMBL9966733 | 0.90 | LTA4H (0.55) | LTA4HHRH3OPRK1 | |
| SCHEMBL9966993 | 0.90 | LTA4H (0.53) | LTA4HHRH3OPRK1 | |
| SCHEMBL9966997 | 0.90 | LTA4H (0.53) | LTA4HHRH3OPRK1 | |
| Hydrochloric Acid SCHEMBL9940122 | 0.90 | LTA4H (0.51) | LTA4HHRH3OPRK1 | |
| Hydrochloric Acid SCHEMBL9942188 | 0.89 | LTA4H (0.54) | LTA4HHRH3OPRK1 | |
| Hydrochloric Acid SCHEMBL9940212 | 0.89 | LTA4H (0.52) | LTA4HHRH3OPRK1 | |
| SCHEMBL9967017 | 0.89 | ESR1 (0.54) | KDM4EHRH3SIGMAR1 | |
| SCHEMBL9966990 | 0.88 | LTA4H (0.54) | LTA4HALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |