Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967016 | 0.91 | ESR1 (0.64) | ESR1ESR2F2 | |
| SCHEMBL9967048 | 0.90 | ESR1 (0.66) | ESR1ESR2F2 | |
| SCHEMBL9967050 | 0.90 | ESR1 (0.56) | ESR1ESR2F2 | |
| SCHEMBL9967047 | 0.90 | ESR1 (0.66) | ESR1ESR2F2 | |
| SCHEMBL9967056 | 0.89 | ESR1 (0.54) | ESR1ESR2F2MEN1KMT2A | |
| SCHEMBL9966883 | 0.89 | ESR1 (0.61) | ESR1ESR2KDM4EF2SIGMAR1 | |
| SCHEMBL9966794 | 0.89 | KDM4E (0.48) | KDM4ESIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9940208 | 0.88 | KDM4E (0.47) | KDM4ESIGMAR1 | |
| SCHEMBL9966995 | 0.88 | ESR1 (0.57) | ESR1ESR2KDM4EF2SIGMAR1 | |
| SCHEMBL9966974 | 0.87 | ESR1 (0.56) | ESR1ESR2KDM4EF2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |