Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21986550 | 0.98 | SMN1; SMN2 (0.59) | SMN1; SMN2KCNH2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL517979 | 0.90 | KCNH2 (0.58) | SMN1; SMN2KCNH2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL22564633 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2KCNH2CHRM2MEN1KMT2A | |
| SCHEMBL9777453 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2CHRM2MEN1KMT2ACXCR4 | |
| SCHEMBL9777407 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2CHRM2MEN1KMT2ACXCR4 | |
| SCHEMBL10483884 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2CHRM2MEN1KMT2ACXCR4 | |
| SCHEMBL10483914 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2CHRM2MEN1KMT2ACXCR4 | |
| SCHEMBL943003 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP2C19MEN1KMT2ACXCR4 | |
| SCHEMBL1038536 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2MEN1KMT2ACXCR4MAOA | |
| SCHEMBL3265299 | 0.78 | SMN1; SMN2 (0.81) | SMN1; SMN2MEN1KMT2AMAOAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079583-A1 | SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS | AARHUS UNIVERSITET (DK) | 2012-06-21 | — | — | WO | disclosed |