SCHEMBL996765

SCHEMBL996765

CCCCCCCCCCCCc1ccc2c(c1)Cc1cc(-c3ccc(-c4ccc(-c5ccc6c(c5)Cc5cc(CCCCCCCCCCCC)ccc5-6)s4)s3)ccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 7/20 0.44
HTR2A P28223 2/20 0.43
DRD2 P14416 1/20 0.43
SLC6A2 P23975 1/20 0.43
HTR2C P28335 1/20 0.43
SLC6A4 P31645 1/20 0.43
GPR3 P46089 1/20 0.40
RARB P10826 2/20 0.39
PRF1 P14222 1/20 0.38
ACHE P22303 1/20 0.38
KDM4E B2RXH2 1/20 0.38
RAB9A P51151 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
S1PR3 Q99500 4/20 0.37
S1PR4 O95977 2/20 0.37
S1PR5 Q9H228 2/20 0.37
TNNC1 P63316 3/20 0.37
SGPL1 O95470 1/20 0.37
GPR183 P32249 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2464850 1.00 S1PR1 (0.44) S1PR1HTR2ADRD2SLC6A2HTR2C
SCHEMBL8147208 0.85 HSD17B10 (0.49) HTR2ADRD2SLC6A2HTR2CSLC6A4
SCHEMBL4900272 0.84 HTR2A (0.55) S1PR1HTR2ADRD2SLC6A2HTR2C
SCHEMBL30369240 0.84 HTR2A (0.55) S1PR1HTR2ADRD2SLC6A2HTR2C
SCHEMBL4898274 0.84 HTR2A (0.55) S1PR1HTR2ADRD2SLC6A2HTR2C
SCHEMBL4895814 0.84 HTR2A (0.55) S1PR1HTR2ADRD2SLC6A2HTR2C
SCHEMBL4887234 0.84 HTR2A (0.55) S1PR1HTR2ADRD2SLC6A2HTR2C
SCHEMBL31228811 0.83 HTR2A (0.52) S1PR1HTR2ADRD2SLC6A2HTR2C
SCHEMBL2930325 0.83 HTR2A (0.52) S1PR1HTR2ADRD2SLC6A2HTR2C
SCHEMBL9844235 0.79 KDM4E (0.48) S1PR1HTR2ADRD2SLC6A2HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2926376-B1 AMBIPOLAR VERTICAL FIELD EFFECT TRANSISTOR UNIV FLORIDA (US) 2017-11-08 EP disclosed
US-9601707-B2 Ambipolar vertical field effect transistor UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2017-03-21 US disclosed
US-9442087-B2 Organic thin-film transistor sensor arrangements THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2016-09-13 US disclosed
WO-2015195828-A2 IMPLANTABLE CATHETER-DELIVERED NEUROMODULATION DEVICES AND RELATED DEVICES, SYSTEMS, AND METHODS MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L. (LU) 2015-12-23 WO disclosed
US-20150359590-A1 Implantable Catheter-Delivered Neuromodulation Devices and Related Devices, Systems, and Methods MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L. (LU) 2015-12-17 US disclosed
US-20150340631-A1 AMBIPOLAR VERTICAL FIELD EFFECT TRANSISTOR UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-11-26 US disclosed
EP-2926376-A1 AMBIPOLAR VERTICAL FIELD EFFECT TRANSISTOR University of Florida Research Foundation, Inc. (US) 2015-10-07 EP disclosed
US-20150064798-A1 ORGANIC THIN-FILM TRANSISTOR SENSOR ARRANGEMENTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2015-03-05 US disclosed
WO-2014085410-A1 AMBIPOLAR VERTICAL FIELD EFFECT TRANSISTOR UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2014-06-05 WO disclosed
US-20130071289-A1 Biosensor on Thin-Film Transistors KNOLL WOLFGANG (AT) 2013-03-21 US disclosed
EP-2548014-A1 BIOSENSOR ON THIN-FILM TRANSISTORS Knoll, Wolfgang (AT) 2013-01-23 EP disclosed
WO-2011113935-A1 BIOSENSOR ON THIN-FILM TRANSISTORS KNOLL WOLFGANG (AT) 2011-09-22 WO disclosed
EP-2366994-A1 Biosensor on thin-film transistors Knoll, Wolfgang (AT) 2011-09-21 EP disclosed
US-7863603-B1 Organic transistors, organic capacitors, organic semiconductors that can operate at low voltage for use in aqueous environments; dielectric layer made of polyvinylphenol with crosslinking agent that is heat activated; compatibility with different organic semiconductors and gate materials THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2011-01-04 US disclosed