⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15403068 | 0.81 | — | — | |
| SCHEMBL12618069 | 0.78 | — | — | |
| SCHEMBL31742422 | 0.75 | — | — | |
| SCHEMBL726548 | 0.73 | — | — | |
| SCHEMBL18893489 | 0.73 | CYP2C19 (0.30) | — | |
| SCHEMBL13692809 | 0.71 | — | — | |
| SCHEMBL824112 | 0.69 | — | — | |
| SCHEMBL12570877 | 0.69 | — | — | |
| SCHEMBL7865165 | 0.69 | — | — | |
| SCHEMBL4441846 | 0.69 | GABRR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372496-A1 | TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS | C4 THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | US | disclosed |
| US-20210093618-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2021-04-01 | — | — | US | disclosed |
| US-10294243-B2 | Bicyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-05-21 | — | — | US | disclosed |
| US-9694002-B2 | Substituted benzamides and methods of use thereof | GENENTECH, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170101422-A1 | Bicyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | US | disclosed |
| US-20170101422-A1 | Bicyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | US | disclosed |
| US-20170087136-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2017-03-30 | — | — | US | disclosed |
| US-9546164-B2 | Substituted benzamides and methods of use thereof | GENENTECH, INC. (US) | 2017-01-17 | — | — | US | disclosed |
| US-20150252038-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2015-09-10 | — | — | US | disclosed |
| US-20150173359-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER IP GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20110218103-A1 | Fluoroalkyl-substituted 2-amidobenzimidazoles | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | disclosed |
| US-20110218103-A1 | Fluoroalkyl-substituted 2-amidobenzimidazoles | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | disclosed |
| US-20100284939-A1 | HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME | LIVING PROOF, INC. (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100284953-A1 | HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME | LIVING PROOF, INC. (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100278769-A1 | HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR | LIVING PROOF, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-7785575-B2 | controlling frizz in scalp hair by applying a mixture of a nonpolymeric fluorinated ester such as hexafluoroisopropyl 2-fluoroacrylate, water, emulsifiers and flow control agents | LIVING PROOF, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7763240-B2 | Hair care compositions and methods of treating hair using same | LIVING PROOF, INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-20090226382-A1 | HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME | LIVING PROOF, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090191141-A1 | HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME | LIVING PROOF, INC. (US) | 2009-07-30 | — | — | US | disclosed |
| US-20090104136-A1 | HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME | LIVING PROOF, INC. | 2009-04-23 | — | — | US | disclosed |