Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 6/20 | 0.53 |
| ▸ | CA1 | P00915 | 6/20 | 0.53 |
| ▸ | CA2 | P00918 | 6/20 | 0.53 |
| ▸ | CA7 | P43166 | 6/20 | 0.53 |
| ▸ | CA9 | Q16790 | 6/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9999707 | 0.86 | CA12 (0.72) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL17150210 | 0.80 | CA12 (0.47) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL13555097 | 0.79 | TSHR (0.77) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL19203928 | 0.79 | CA12 (0.50) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL346578 | 0.74 | TSHR (0.67) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL13493184 | 0.74 | CYP4F2 (0.53) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL8396843 | 0.73 | CA1 (0.68) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL15196515 | 0.73 | CYP4F2 (0.58) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL322149 | 0.72 | CA12 (0.69) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL20780788 | 0.72 | KDM4E (0.49) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083059-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-06-21 | — | — | WO | disclosed |