Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967911 | 0.80 | TSHR (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9999707 | 0.80 | CA12 (0.72) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8733285 | 0.77 | TSHR (0.69) | TSHRALDH1A1KMT2AMAPTKDM4E | |
| Bicarbonate SCHEMBL27963013 | 0.74 | TSHR (0.65) | TSHRALDH1A1KMT2AHSD17B10LMNA | |
| SCHEMBL19203928 | 0.74 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1193719 | 0.73 | CA12 (0.66) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8191128 | 0.72 | LMNA (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10487681 | 0.72 | FLT1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13469254 | 0.71 | TSHR (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4527898 | 0.70 | KMT2A (0.49) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015152368-A1 | OXAZOLIDINONE AND OXAZINANONE DERIVATIVES | 大正製薬株式会社 | 2015-10-08 | — | — | WO | disclosed |