Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931144 | 0.92 | CCR2 (0.81) | CCR2PKMTP53BRAF | |
| SCHEMBL9930276 | 0.84 | CCR2 (0.77) | CCR2PKMTP53BRAF | |
| SCHEMBL9968068 | 0.83 | CCR2 (0.64) | CCR2PKMBRAF | |
| SCHEMBL9968200 | 0.82 | CCR2 (0.62) | CCR2PKMTP53 | |
| SCHEMBL9973039 | 0.81 | CCR2 (0.76) | CCR2PKMTP53 | |
| SCHEMBL9968225 | 0.81 | CCR2 (0.72) | CCR2PKMTP53BRAF | |
| SCHEMBL9930749 | 0.81 | CCR2 (1.00) | CCR2PKMBRAF | |
| SCHEMBL9930411 | 0.80 | CCR2 (1.00) | CCR2PKMBRAF | |
| SCHEMBL9931494 | 0.79 | CCR2 (1.00) | CCR2PKMBRAF | |
| SCHEMBL9930852 | 0.79 | CCR2 (0.81) | CCR2PKMBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082633-A1 | NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-21 | — | — | WO | disclosed |