Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 15/20 | 0.61 |
| ▸ | BRAF | P15056 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931003 | 0.89 | CCR2 (0.76) | CCR2BRAFPKMMEN1LMNA | |
| SCHEMBL9968068 | 0.81 | CCR2 (0.64) | CCR2BRAFPKMMEN1KMT2A | |
| SCHEMBL9930692 | 0.78 | CCR2 (0.78) | CCR2BRAFPKMMEN1LMNA | |
| SCHEMBL9968265 | 0.78 | CCR2 (0.66) | CCR2BRAFPKMMEN1LMNA | |
| SCHEMBL9930749 | 0.77 | CCR2 (1.00) | CCR2BRAFPKMMEN1LMNA | |
| SCHEMBL9931289 | 0.77 | CCR2 (0.76) | CCR2BRAFPKM | |
| SCHEMBL9930882 | 0.75 | CCR2 (0.72) | CCR2BRAFPKMHTT | |
| SCHEMBL9931465 | 0.75 | CCR2 (0.81) | CCR2BRAFPKMMEN1LMNA | |
| SCHEMBL9930632 | 0.75 | CCR2 (0.72) | CCR2BRAFPKMMEN1LMNA | |
| SCHEMBL9930852 | 0.75 | CCR2 (0.81) | CCR2BRAFPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082633-A1 | NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-21 | — | — | WO | disclosed |