SCHEMBL9968176

SCHEMBL9968176

Cc1cc(-n2c3ccccc3c3cc(CC(C)(C)C)ncc32)ccc1-c1ccc(-n2c3ccccc3c3cc(CC(C)(C)C)ncc32)cc1C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CNR2 P34972 1/20 0.31
PPARG P37231 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21085499 0.85 KDM4E (0.49) KDM4EATML3MBTL1CNR2PPARG
SCHEMBL9968202 0.82 L3MBTL1 (0.37) KDM4EATML3MBTL1CNR2PPARG
SCHEMBL63587 0.78 KDM4E (0.52) KDM4EATML3MBTL1PPARGPOLB
SCHEMBL29462706 0.78 KDM4E (0.52) KDM4EATML3MBTL1PPARGPOLB
SCHEMBL29349946 0.78 KDM4E (0.52) KDM4EATML3MBTL1PPARGPOLB
SCHEMBL9968240 0.76 PPARG (0.37) KDM4EATML3MBTL1PPARG
SCHEMBL10100831 0.75 KDM4E (0.48) KDM4EATML3MBTL1PPARGPOLB
SCHEMBL13049632 0.75 KDM4E (0.48) KDM4EATML3MBTL1PPARGPOLB
SCHEMBL11965525 0.75 KDM4E (0.40) KDM4EATML3MBTL1POLB
SCHEMBL9968210 0.74 PARP1 (0.35) KDM4EATML3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed