SCHEMBL9968182

SCHEMBL9968182

c1ccc([Si](c2ccc(-n3c4ccccc4c4cnccc43)cc2)(c2ccc(-n3c4ccccc4c4cnccc43)cc2)c2ccc(-n3c4ccccc4c4cnccc43)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAOA P21397 4/20 0.48
MAOB P27338 4/20 0.48
ACHE P22303 2/20 0.48
CYP2D6 P10635 1/20 0.42
DDB1 Q16531 1/20 0.38
CRBN Q96SW2 1/20 0.38
CDK4 P11802 1/20 0.38
CDK6 Q00534 1/20 0.38
PTPN1 P18031 2/20 0.36
ALDH1A1 P00352 1/20 0.36
FGFR1 P11362 1/20 0.36
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
SLC6A2 P23975 1/20 0.35
REN P00797 1/20 0.34
TOP2A P11388 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19837801 1.00 KDM4E (0.50) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL9968177 1.00 KDM4E (0.50) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL24988434 0.93 KDM4E (0.44) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL19837794 0.91 KDM4E (0.50) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL19837791 0.91 KDM4E (0.50) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL12098614 0.87 KDM4E (0.67) KDM4EATML3MBTL1MAOAMAOB
SCHEMBL29350395 0.87 L3MBTL1 (0.65) KDM4EATML3MBTL1PTPN1ALDH1A1
SCHEMBL12108663 0.87 L3MBTL1 (0.65) KDM4EATML3MBTL1PTPN1ALDH1A1
SCHEMBL65379 0.87 L3MBTL1 (0.65) KDM4EATML3MBTL1PTPN1ALDH1A1
SCHEMBL29552202 0.87 L3MBTL1 (0.65) KDM4EATML3MBTL1PTPN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed