SCHEMBL9968267

SCHEMBL9968267

CC(C)(C)Cc1ccc2c(c1)c1nc(C(c3ccccc3)(c3ccccc3)c3ccc4c(n3)c3cc(CC(C)(C)C)ccc3n4-c3ccccc3)ccc1n2-c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PLA2G4A P47712 1/20 0.32
ATM Q13315 1/20 0.32
PDE7A Q13946 1/20 0.31
PDE7B Q9NP56 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26998656 0.80 KDM4E (0.46) ALDH1A1KDM4EL3MBTL1MEN1KMT2A
SCHEMBL22177168 0.76 KDM4E (0.55) ALDH1A1KDM4EL3MBTL1MEN1KMT2A
SCHEMBL24272555 0.75 KDM4E (0.44) ALDH1A1KDM4EL3MBTL1MEN1KMT2A
SCHEMBL9968152 0.74 MAPK8 (0.35) ALDH1A1KDM4EL3MBTL1MEN1KMT2A
SCHEMBL9968190 0.74
SCHEMBL9968144 0.73 KDM4E (0.38) ALDH1A1KDM4EL3MBTL1MEN1KMT2A
SCHEMBL9968148 0.73 KDM4E (0.38) ALDH1A1KDM4EL3MBTL1MEN1KMT2A
SCHEMBL9968189 0.73 PTGER4 (0.30) KDM4EL3MBTL1ATM
SCHEMBL10206247 0.72 KDM4E (0.36) ALDH1A1KDM4EL3MBTL1HPGDPLA2G4A
SCHEMBL9968242 0.72 KDM4E (0.34) KDM4EL3MBTL1ATMPDE7APDE7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed