SCHEMBL9968152

SCHEMBL9968152

CC(C)(C)Cc1ccc2c(c1)c1ccc(C(C)(C)c3ccc4c5cc(CC(C)(C)C)ccc5n(-c5ccccc5)c4n3)nc1n2-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 5/20 0.35
MAPK9 P45984 2/20 0.35
MAPK10 P53779 2/20 0.35
PLA2G4A P47712 1/20 0.33
ALDH1A1 P00352 3/20 0.33
PDE7A Q13946 1/20 0.32
PDE7B Q9NP56 1/20 0.32
CNR2 P34972 1/20 0.31
ECE1 P42892 1/20 0.31
MAT2A P31153 3/20 0.31
PGR P06401 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 3/20 0.30
HPGD P15428 2/20 0.30
L3MBTL1 Q9Y468 2/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9968150 0.85 PLA2G4A (0.33) PLA2G4AALDH1A1PDE7APDE7BECE1
SCHEMBL26998656 0.82 KDM4E (0.46) MAPK8MAPK9PLA2G4AALDH1A1PGR
SCHEMBL24272555 0.79 KDM4E (0.44) MAPK8MAPK9PLA2G4AALDH1A1MAT2A
SCHEMBL22177168 0.78 KDM4E (0.55) MAPK8MAPK9PLA2G4AALDH1A1CNR2
SCHEMBL9968267 0.74 ALDH1A1 (0.34) PLA2G4AALDH1A1PDE7APDE7BCNR2
SCHEMBL22986683 0.72 KDM4E (0.55) MAPK8MAPK9ALDH1A1PGRMEN1
SCHEMBL25460096 0.72 KDM4E (0.37) MAPK8MAPK9PLA2G4AALDH1A1MAT2A
SCHEMBL21085498 0.72 KDM4E (0.46) MAPK8MAPK9ALDH1A1PDE7APDE7B
SCHEMBL25503416 0.72 KDM4E (0.46) MAPK8MAPK9PLA2G4AALDH1A1CNR2
SCHEMBL10206247 0.71 KDM4E (0.36) MAPK8PLA2G4AALDH1A1MAT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed