SCHEMBL997016

SCHEMBL997016

Cc1cc(C(C)(C)C)c(C(Oc2ccc(C(C)(C)C)cc2C(C)(C)C)C(CO)(CO)CO)c(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CA2 P00918 1/20 0.33
POLB P06746 1/20 0.33
TYR P14679 1/20 0.33
TRPV1 Q8NER1 1/20 0.32
APEX1 P27695 1/20 0.32
USP2 O75604 1/20 0.32
CYP2C19 P33261 2/20 0.32
HSPA5 P11021 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP2C9 P11712 1/20 0.31
HIF1A Q16665 1/20 0.31
SCN10A Q9Y5Y9 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
MRGPRX4 Q96LA9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27801956 0.86 RECQL (0.32) CA2TRPV1APEX1SCN10A
SCHEMBL996129 0.86 SMN1; SMN2 (0.35) SMN1; SMN2ALDH1A1USP2HIF1ACNR1
SCHEMBL75189 0.83 CYP2C19 (0.33) KDM4ESMN1; SMN2ALDH1A1CA2TRPV1
SCHEMBL996128 0.82 CNR2 (0.44) CNR1CNR2
SCHEMBL28276179 0.82 MEN1 (0.33) KDM4ESMN1; SMN2ALDH1A1CA2TRPV1
Phosphine SCHEMBL8374080 0.82 TRPV1 (0.33) KDM4ESMN1; SMN2ALDH1A1CA2TRPV1
SCHEMBL313325 0.80 TRPV1 (0.34) KDM4EALDH1A1TRPV1APEX1CYP2C19
SCHEMBL190993 0.80 TRPV1 (0.34) KDM4EALDH1A1TRPV1APEX1CYP2C19
SCHEMBL77036 0.79 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL15090602 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604447-B1 POLYAMIDE COMPOSITION AND MOLDED ARTICLE ASAHI CHEMICAL IND (JP) 2023-08-16 EP disclosed
WO-2023120457-A1 POLYAMIDE COMPOSITION 株式会社クラレ 2023-06-29 WO disclosed
US-11192979-B2 Polyamide composition and molded article ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-12-07 US disclosed
US-10815377-B2 Resin composition, resin molding, method for manufacturing plated resin molding, and method for manufacturing antenna-equipped portable electronic device part MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2020-10-27 US disclosed
EP-3081598-B1 POLYAMIDE COMPOSITION, MOLDED ARTICLE, REFLECTIVE BOARD FOR LEDS, AND METHOD FOR PREVENTING HEAT-INDUCED REFLECTIVITY REDUCTION ASAHI CHEMICAL IND (JP) 2020-06-10 EP disclosed
US-20200087458-A1 POLYAMIDE COMPOSITION AND MOLDED ARTICLE ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-03-19 US disclosed
EP-3604447-A1 POLYAMIDE COMPOSITION AND MOLDED ARTICLE Asahi Kasei Kabushiki Kaisha (JP) 2020-02-05 EP disclosed
US-20180298190-A1 RESIN COMPOSITION, RESIN MOLDING, METHOD FOR MANUFACTURING PLATED RESIN MOLDING, AND METHOD FOR MANUFACTURING ANTENNA-EQUIPPED PORTABLE ELECTRONIC DEVICE PART MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2018-10-18 US disclosed
US-9611356-B2 Copolymer polyamide ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-04-04 US disclosed
EP-2687555-B1 POLYAMIDE AND POLYAMIDE COMPOSITION ASAHI CHEMICAL IND (JP) 2016-12-14 EP disclosed
EP-2476717-A1 POLYAMIDE AND POLYAMIDE COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2012-07-18 EP disclosed
US-20120165466-A1 POLYAMIDE AND POLYAMIDE COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-06-28 US disclosed
US-20110028614-A1 POLYAMIDE, POLYAMIDE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-02-03 US disclosed
EP-2270067-A1 POLYAMIDE, POLYAMIDE COMPOSITION AND METHOD FOR PRODUCING POLYAMIDE Asahi Kasei Chemicals Corporation (JP) 2011-01-05 EP disclosed
US-4888371-A HEAT RESISTANCE, LIGHT RESISTANCE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1989-12-19 US disclosed
EP-0255097-A2 Process for improving resistance to deterioration when exposed to sterilizing radiation of polyolefin resins ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1988-02-03 EP disclosed
EP-0143464-B1 PENTAERYTHRITOL-SPIRO-BIS-PHOSPHITE COMPOSITIONS HAVING IMPROVED HYDROLYTIC STABILITY Argus Chemical Corporation (US) 1987-07-08 EP disclosed
EP-0143464-A2 Pentaerythritol-spiro-bis-phosphite compositions having improved hydrolytic stability Argus Chemical Corporation (US) 1985-06-05 EP disclosed
US-4371647-A 2,6-Di-tertiary butyl phenyl pentaerythritol spiro bis-phosphites enhancing the stability to heat and light of synthetic resin ADEKA ARGUS CHEMICAL CO. LTD. (JP) 1983-02-01 US disclosed
EP-0038876-A1 2,6-Di-tertiary butyl phenyl pentaerythritol spiro bis-phosphites enhancing the stability to heat and light of synthetic resins, stabilizer compositions comprising phenolic antioxidants and such phosphites, and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-11-04 EP disclosed