SCHEMBL9970462

SCHEMBL9970462

Cc1ccc(/C=C/C=C/c2cnc(/C=C/C=C/c3ccc(C)cc3)cn2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
NFE2L2 Q16236 2/20 0.43
RELA Q04206 1/20 0.41
CA1 P00915 1/20 0.41
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
POLB P06746 1/20 0.40
HPGD P15428 1/20 0.40
CYP3A4 P08684 1/20 0.39
FBP1 P09467 1/20 0.38
ALOX5 P09917 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
CYP2A6 P11509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9970463 0.90 KDM4E (0.42) MAPTNFE2L2RELACA1CYP2C9
SCHEMBL317835 0.87 MAPT (0.62) MAPTNFE2L2RELACA1CYP2C9
SCHEMBL317834 0.87 MAPT (0.62) MAPTNFE2L2RELACA1CYP2C9
SCHEMBL9970461 0.85 MAPT (0.46) MAPTNFE2L2RELACA1CYP2C9
SCHEMBL1292955 0.82 NFE2L2 (0.59) MAPTNFE2L2RELACA1CYP2C9
SCHEMBL372652 0.82 NFE2L2 (0.59) MAPTNFE2L2RELACA1CYP2C9
SCHEMBL23458017 0.79 NFE2L2 (0.56) MAPTNFE2L2RELACA1CYP2C9
SCHEMBL29862187 0.79 NFE2L2 (0.56) MAPTNFE2L2RELACA1CYP2C9
SCHEMBL23458148 0.79 NFE2L2 (0.56) MAPTNFE2L2RELACA1CYP2C9
SCHEMBL709611 0.79 MEN1 (0.54) MAPTNFE2L2NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8203139-B2 Organic thin film transistor and organic thin film light-emitting transistor using an organic semiconductor layer having an aromatic hydrocarbon group or an aromatic heterocyclic group in the center thereof IDEMITSU KOSAN CO., LTD (JP) 2012-06-19 US disclosed
US-8203139-B2 Organic thin film transistor and organic thin film light-emitting transistor using an organic semiconductor layer having an aromatic hydrocarbon group or an aromatic heterocyclic group in the center thereof IDEMITSU KOSAN CO., LTD (JP) 2012-06-19 US disclosed
US-20100051919-A1 ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM LIGHT-EMITTING TRANSISTOR IDEMITSU KOSAN CO., LTD. (JP) 2010-03-04 US disclosed
US-20100051919-A1 ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM LIGHT-EMITTING TRANSISTOR IDEMITSU KOSAN CO., LTD. (JP) 2010-03-04 US disclosed