Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470102 | 0.79 | KDM4E (0.56) | KDM4ELMNAHSD17B10BCL2L1BAD | |
| SCHEMBL9938394 | 0.79 | KDM4E (0.43) | KDM4ELMNAHSD17B10BCL2L1BAD | |
| SCHEMBL28380155 | 0.77 | TP53 (0.55) | KDM4EBCL2L1BADMAP4K4CA1 | |
| SCHEMBL9939473 | 0.73 | ESR1 (0.69) | KDM4ELMNAHSD17B10BCL2L1BAD | |
| SCHEMBL1289545 | 0.71 | ESR1 (0.49) | KDM4ELMNAHSD17B10BCL2L1BAD | |
| SCHEMBL9938351 | 0.70 | ESR1 (0.52) | KDM4ELMNAHSD17B10ERN1CA1 | |
| SCHEMBL21409964 | 0.69 | FOLH1 (0.49) | KDM4ELMNAHSD17B10BCL2L1BAD | |
| SCHEMBL29721366 | 0.69 | FOLH1 (0.49) | KDM4ELMNAHSD17B10BCL2L1BAD | |
| SCHEMBL9939221 | 0.69 | ESR1 (0.51) | KDM4ELMNAHSD17B10ERN1SRD5A2 | |
| Methane SCHEMBL29083170 | 0.68 | FOLH1 (0.47) | KDM4ELMNAHSD17B10BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083171-A1 | NOVEL SUBSTITUTED BICYCLIC AROMATIC COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | N30 PHARMACEUTICALS, LLC (US) | 2012-06-21 | — | — | WO | disclosed |