SCHEMBL21409964

SCHEMBL21409964

Nc1c(C(=O)O)ccc(-c2ccc(C(=O)O)cc2)c1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.49
CYP2C8 P10632 3/20 0.47
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
MAPK1 P28482 1/20 0.44
RECQL P46063 1/20 0.44
MAP4K4 O95819 4/20 0.43
SRD5A2 P31213 1/20 0.42
BCL2L1 Q07817 1/20 0.42
BAD Q92934 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29721366 1.00 FOLH1 (0.49) FOLH1CYP2C8TP53TSHRKMT2A
Methane SCHEMBL29083170 0.98 FOLH1 (0.47) FOLH1CYP2C8TP53TSHRKMT2A
SCHEMBL28380155 0.90 TP53 (0.55) FOLH1CYP2C8TP53TSHRALDH1A1
SCHEMBL6316181 0.85 ALDH1A1 (0.54) FOLH1KMT2AALDH1A1MEN1LMNA
SCHEMBL28337319 0.80 FOLH1 (0.55) FOLH1MAP4K4KDM4E
SCHEMBL29792992 0.77 CASP7 (0.58) KMT2AALDH1A1MEN1LMNAPOLB
SCHEMBL690406 0.77 CASP7 (0.58) KMT2AALDH1A1MEN1LMNAPOLB
SCHEMBL28352021 0.76 TP53 (0.43) FOLH1CYP2C8TP53TSHRKMT2A
SCHEMBL14972647 0.76 FOLH1 (0.44) FOLH1CYP2C8TP53TSHRALDH1A1
SCHEMBL20475496 0.76 HNF4A (0.52) FOLH1CYP2C8TP53TSHRSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116459871-A Photocatalyst and preparation method thereof and application of photocatalyst in degradation of phenylsulfone wastewater 南通沃兰化工有限公司 2023-07-21 CN claimed
CN-116459869-A Novel zirconium-based MOF catalyst for preparing hydrogen peroxide by photocatalysis and preparation method and application thereof 华南理工大学 2023-07-21 CN claimed
CN-113801336-B Functionalization of metal organic framework material UiO-67-4Me, functionalized product and application thereof 中山大学 2022-06-24 CN claimed
CN-113801336-A Functionalization of metal organic framework material UiO-67-4Me, functionalized product and application thereof 中山大学 2021-12-17 CN claimed
CN-108070089-B Preparation method of zirconium-based metal organic framework material rich in zirconium ions 中国科学院大连化学物理研究所 2021-03-19 CN claimed
CN-116847983-A Laminated structure and flexible printed circuit board 太阳控股株式会社 2023-10-03 CN disclosed
CN-116459871-A Photocatalyst and preparation method thereof and application of photocatalyst in degradation of phenylsulfone wastewater 南通沃兰化工有限公司 2023-07-21 CN disclosed
CN-116459869-A Novel zirconium-based MOF catalyst for preparing hydrogen peroxide by photocatalysis and preparation method and application thereof 华南理工大学 2023-07-21 CN disclosed
CN-116459869-A Novel zirconium-based MOF catalyst for preparing hydrogen peroxide by photocatalysis and preparation method and application thereof 华南理工大学 2023-07-21 CN disclosed
CN-114381006-B Covalent organic framework material BM-SO with acid-base dual functions 3 H, preparation method and application thereof 江南大学 2022-09-16 CN disclosed
CN-113801336-B Functionalization of metal organic framework material UiO-67-4Me, functionalized product and application thereof 中山大学 2022-06-24 CN disclosed
CN-114381006-A Covalent organic framework material BM-SO with acid-base dual functions3H, preparation method and application thereof 江南大学 2022-04-22 CN disclosed
CN-113801336-A Functionalization of metal organic framework material UiO-67-4Me, functionalized product and application thereof 中山大学 2021-12-17 CN disclosed
CN-106796395-B Dry film and flexible printed circuit board 太阳油墨制造株式会社 2020-12-18 CN disclosed
CN-106796400-B Laminated structure 太阳油墨制造株式会社 2020-11-03 CN disclosed
WO-2019189637-A1 NOVEL LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2019-10-03 WO disclosed
CN-106124470-B A kind of fluorescent reagent of detection rare earth Tb ions 马鞍山金安环境科技有限公司 2018-09-14 CN disclosed
CN-106124470-A A kind of fluorometric reagent detecting rare earth Tb ion 徐伟鹏 2016-11-16 CN disclosed