Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 4/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16078200 | 0.84 | EGFR (0.40) | EGFRKDM4EALDH1A1 | |
| SCHEMBL18937038 | 0.83 | EGFR (0.34) | HTR1BEGFRALDH1A1 | |
| SCHEMBL1231181 | 0.81 | EGFR (0.40) | EGFRALDH1A1 | |
| SCHEMBL1840926 | 0.81 | EGFR (0.42) | EGFRHTR6KDM4EALDH1A1 | |
| SCHEMBL1840855 | 0.81 | KAT2B (0.45) | HTR1BEGFRHTR6CHRNB2CHRNA4 | |
| SCHEMBL3835527 | 0.81 | EGFR (0.38) | EGFRCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL1840928 | 0.80 | EGFR (0.39) | EGFRALDH1A1 | |
| SCHEMBL19688875 | 0.80 | EGFR (0.39) | EGFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL1151493 | 0.80 | EGFR (0.39) | EGFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL3318724 | 0.80 | EGFR (0.41) | EGFRHTR6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012080321-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |