Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3318724 | 0.98 | EGFR (0.41) | EGFRALDH1A1DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL1841281 | 0.98 | EGFR (0.41) | EGFRALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL16078200 | 0.88 | EGFR (0.40) | EGFRALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL17849035 | 0.86 | NCF1 (0.39) | EGFRALDH1A1DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL17849030 | 0.84 | NCF1 (0.38) | EGFRALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL3850868 | 0.84 | EGFR (0.42) | EGFRALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL13016469 | 0.82 | ALDH1A1 (0.37) | EGFRALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL33951 | 0.81 | EGFR (0.41) | EGFRALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL1231181 | 0.81 | EGFR (0.40) | EGFRALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL9970803 | 0.81 | HTR1B (0.41) | EGFRALDH1A1KDM4EHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792606-B1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | OREAL (FR) | 2011-05-18 | — | — | EP | claimed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | claimed |
| EP-3474815-A1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | L'OREAL (FR) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017220676-A1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | L'OREAL (FR) | 2017-12-28 | — | — | WO | disclosed |
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| EP-1792606-B1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | OREAL (FR) | 2011-05-18 | — | — | EP | disclosed |
| EP-1792606-B1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | OREAL (FR) | 2011-05-18 | — | — | EP | disclosed |
| US-7857864-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative | L'OREAL S.A. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-7857864-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative | L'OREAL S.A. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-7635394-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2009-12-22 | — | — | US | disclosed |
| US-7635394-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2009-12-22 | — | — | US | disclosed |
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | KRT18, MARK1, MARK2 | EGFR 2984/4885ALDH1A1 683/4885DRD2 2287/4885 |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | KRT18, MARK1, MARK2 | EGFR 3043/4885ALDH1A1 711/4885DRD2 2289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.