Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 16/20 | 0.56 |
| ▸ | SRC | P12931 | 16/20 | 0.56 |
| ▸ | LYN | P07948 | 15/20 | 0.56 |
| ▸ | KDR | P35968 | 15/20 | 0.56 |
| ▸ | INSR | P06213 | 14/20 | 0.56 |
| ▸ | HCK | P08631 | 13/20 | 0.56 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586049 | 1.00 | LCK (0.56) | LCKSRCLYNKDRINSR | |
| SCHEMBL9967472 | 0.92 | LYN (0.47) | LCKSRCLYNKDRINSR | |
| SCHEMBL3590283 | 0.89 | LCK (0.58) | LCKSRCLYNKDRINSR | |
| SCHEMBL3589676 | 0.88 | SRC (0.61) | LCKSRCLYNKDRINSR | |
| SCHEMBL3585481 | 0.88 | SRC (0.63) | LCKSRCLYNKDRINSR | |
| SCHEMBL3594776 | 0.87 | SRC (0.64) | LCKSRCLYNKDRINSR | |
| SCHEMBL3594784 | 0.87 | SRC (0.63) | LCKSRCLYNKDRINSR | |
| SCHEMBL9967467 | 0.86 | LCK (0.58) | LCKSRCLYNKDRINSR | |
| SCHEMBL3591712 | 0.85 | LCK (0.66) | LCKSRCLYNKDRINSR | |
| SCHEMBL3591827 | 0.85 | SRC (0.61) | LCKSRCLYNKDRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202876-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2012-06-19 | — | — | US | disclosed |