SCHEMBL9970932

SCHEMBL9970932

COC(C)COc1ccc(-c2ccc(OCC3CO3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
TP53 P04637 3/20 0.51
TSHR P16473 3/20 0.51
MAPT P10636 3/20 0.51
HPGD P15428 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
HIF1A Q16665 2/20 0.51
CYP1A2 P05177 1/20 0.51
PPARG P37231 1/20 0.51
TDP1 Q9NUW8 1/20 0.50
PKM P14618 2/20 0.49
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
CYP3A4 P08684 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
GLA P06280 1/20 0.40
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10052339 0.91 ALDH1A1 (0.51) ALDH1A1TP53TSHRMAPTHPGD
SCHEMBL14417527 0.89 ALDH1A1 (0.49) ALDH1A1TP53TSHRMAPTHPGD
SCHEMBL20217118 0.89 ALDH1A1 (0.49) ALDH1A1TP53TSHRMAPTHPGD
SCHEMBL10052353 0.87 ALDH1A1 (0.48) ALDH1A1TP53TSHRMAPTHPGD
SCHEMBL13050068 0.86 KMT2A (0.74) ALDH1A1TP53TSHRMAPTHPGD
SCHEMBL12288893 0.86 ALDH1A1 (0.61) ALDH1A1TP53TSHRMAPTHPGD
SCHEMBL12502215 0.86 KMT2A (0.74) ALDH1A1TP53TSHRMAPTHPGD
SCHEMBL22837910 0.84 ALDH1A1 (0.53) ALDH1A1TP53TSHRMAPTHPGD
SCHEMBL21202704 0.82 TDP1 (0.70) ALDH1A1TP53TSHRMAPTHPGD
SCHEMBL2720991 0.82 TDP1 (0.70) ALDH1A1TP53TSHRMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120270994-A1 AROMATIC RING-CONTAINING POLYMER FOR UNDERLAYER OF RESIST AND RESIST UNDERLAYER COMPOSITION INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-10-25 US disclosed
US-20120168894-A1 HARD MASK COMPOSITION, METHOD OF FORMING A PATTERN, AND SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE INCLUDING THE PATTERN CHEIL INDUSTRIES, INC. (KR) 2012-07-05 US disclosed
US-20120153511-A1 HARDMASK COMPOSITION AND METHOD OF FORMING PATTERNS AND SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE INCLUDING THE PATTERNS CHEIL INDUSTRIES, INC. (KR) 2012-06-21 US disclosed
US-20120153424-A1 HARDMASK COMPOSITION, METHOD OF FORMING A PATTERN USING THE SAME, AND SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE INCLUDING THE PATTERN CHEIL INDUSTRIES, INC. (KR) 2012-06-21 US disclosed
US-8153349-B2 Polymer composition, hardmask composition having antireflective properties, and associated methods CHEIL INDUSTRIES, INC. (KR) 2012-04-10 US disclosed
US-20110155944-A1 AROMATIC RING-CONTAINING COMPOUND FOR A RESIST UNDERLAYER AND RESIST UNDERLAYER COMPOSITION CHEIL INDUSTRIES, INC. (KR) 2011-06-30 US disclosed
US-20110117501-A1 RESIST UNDERLAYER POLYMER, RESIST UNDERLAYER COMPOSITION INCLUDING THE SAME, AND METHOD OF PATTERNING USING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-05-19 US disclosed
US-20110027722-A1 AROMATIC RING-CONTAINING POLYMER FOR RESIST UNDERLAYER, RESIST UNDERLAYER COMPOSITION INCLUDING THE SAME, AND METHOD OF PATTERNING DEVICE USING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110155944-A1 AROMATIC RING-CONTAINING COMPOUND FOR A RESIST UNDERLAYER AND RESIST UNDERLAYER COMPOSITION ABCC1, C5, SLC11A2 ALDH1A1 2908/4885TP53 4550/4885TSHR 3507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.