Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18199753 | 0.82 | CHRM3 (1.00) | CHRM3 | |
| SCHEMBL18199754 | 0.81 | CHRM3 (1.00) | CHRM3 | |
| SCHEMBL4895502 | 0.80 | CHRM3 (0.64) | CHRM3CHRM1AGTR2C3AR1 | |
| SCHEMBL15015232 | 0.80 | CHRM3 (0.64) | CHRM3AGTR2 | |
| SCHEMBL18199757 | 0.79 | CHRM3 (1.00) | CHRM3 | |
| SCHEMBL15127557 | 0.79 | CHRM3 (0.74) | CHRM3 | |
| SCHEMBL8670678 | 0.78 | MAOA (0.55) | — | |
| SCHEMBL27933777 | 0.77 | CHRM3 (0.72) | CHRM3 | |
| SCHEMBL4875919 | 0.76 | CHRM3 (0.67) | CHRM3CHRM1 | |
| SCHEMBL20202492 | 0.76 | CHRM3 (1.00) | CHRM3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120232053-A1 | QUATERNARY AMMONIUM COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2012-09-13 | — | — | US | disclosed |
| US-8202891-B2 | Quaternary ammonium compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20080269190-A1 | Chronic obstructive pulmonary disease; asthma | THERAVANCE, INC. | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232053-A1 | QUATERNARY AMMONIUM COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | CHRM2, CHRM5, CHRM1 | CHRM3 4/4885CHRM1 3/4885AGTR2 27/4885 |
| US-20080269190-A1 | Chronic obstructive pulmonary disease; asthma | CHRM2, CHRM5, CHRM3 | CHRM3 3/4885CHRM1 4/4885AGTR2 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.