Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14083175 | 0.81 | — | — | |
| SCHEMBL13220403 | 0.79 | — | — | |
| SCHEMBL22104721 | 0.79 | — | — | |
| SCHEMBL12786458 | 0.75 | — | — | |
| SCHEMBL12488303 | 0.75 | — | — | |
| SCHEMBL8348123 | 0.75 | ALDH1A1 (0.30) | ALDH1A1TP53TSHR | |
| SCHEMBL19446094 | 0.75 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL16728975 | 0.73 | — | — | |
| SCHEMBL12648948 | 0.72 | — | — | |
| SCHEMBL23253510 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669030-B2 | Hydantoin derivatives as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |
| EP-2313412-B1 | NOVEL DERIVATIVES OF PYRROLOINDOLE INHIBITORS OF HSP90, COMPOSITIONS CONTAINING SAME, AND USE THEREOF | SANOFI SA (FR) | 2013-01-02 | — | — | EP | disclosed |
| WO-2012081665-A1 | SUBSTANCE CAPABLE OF INHIBITING GLYCINE TRANSPORTER | 大正製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |