Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK1 | P19367 | 9/20 | 0.45 |
| ▸ | HK2 | P52789 | 9/20 | 0.45 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971328 | 0.92 | HK1 (0.50) | HK1HK2GCKDRD2DRD4 | |
| SCHEMBL9971386 | 0.86 | HK1 (0.48) | HK1HK2GCKDRD2DRD4 | |
| SCHEMBL9971310 | 0.86 | HK1 (0.56) | HK1HK2GCK | |
| SCHEMBL9971335 | 0.85 | HK1 (0.40) | HK1HK2GCK | |
| SCHEMBL9938498 | 0.83 | HK1 (0.56) | HK1HK2GCK | |
| SCHEMBL9938496 | 0.83 | HK1 (0.56) | HK1HK2GCK | |
| SCHEMBL9971381 | 0.81 | ALDH1A1 (0.41) | HK1HK2 | |
| SCHEMBL9971365 | 0.73 | HK1 (0.65) | HK1HK2GCKDRD2DRD4 | |
| SCHEMBL9938660 | 0.73 | HK1 (0.72) | HK1HK2GCK | |
| SCHEMBL9937795 | 0.72 | HK1 (0.49) | HK1HK2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083145-A1 | GLUCOSAMINE DERIVATIVES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-06-21 | — | — | WO | disclosed |