Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457852 | 0.94 | — | — | |
| SCHEMBL14038169 | 0.93 | KCNH2 (0.31) | KCNH2GAAXBP1ATMNPSR1 | |
| SCHEMBL172351 | 0.93 | GAA (0.35) | KCNH2GAAXBP1ATMNPSR1 | |
| SCHEMBL23544539 | 0.93 | GAA (0.35) | KCNH2GAAXBP1ATMNPSR1 | |
| SCHEMBL2813206 | 0.92 | GAA (0.31) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL17791350 | 0.88 | GAA (0.34) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL16803235 | 0.88 | GAA (0.34) | KCNH2GAAXBP1ATMNPSR1 | |
| SCHEMBL12345496 | 0.88 | GAA (0.32) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL13677623 | 0.88 | GAA (0.32) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL805448 | 0.87 | NR5A2 (0.32) | GAAXBP1ATMNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120224124-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-09-06 | — | — | US | disclosed |
| US-8202584-B2 | Liquid-crystalline medium and liquid-crystal display | MERCK PATENT GMBH (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20100252777-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-10-07 | — | — | US | disclosed |
| US-7740769-B2 | Liquid crystal compound, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 2010-06-22 | — | — | US | disclosed |
| US-7678432-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2010-03-16 | — | — | US | disclosed |
| US-7425355-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2008-09-16 | — | — | US | disclosed |
| US-20080088789-A1 | Liquid-crystalline medium | MERCK PATENT GMBH | 2008-04-17 | — | — | US | disclosed |
| US-20070187644-A1 | Liquid crystal compound, liquid crystal composition, and liquid crystal display device | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120224124-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | VCL, LPXN, LCP1 | KCNH2 3215/4885GAA 3052/4885XBP1 4290/4885 |
| US-20080088789-A1 | Liquid-crystalline medium | F12, CHRM1, NEFM | KCNH2 3340/4885GAA 1863/4885XBP1 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.