Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038169 | 0.94 | KCNH2 (0.31) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL10037921 | 0.94 | — | — | |
| SCHEMBL9971643 | 0.92 | KCNH2 (0.32) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL23544539 | 0.92 | GAA (0.35) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL172351 | 0.92 | GAA (0.35) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL12431272 | 0.91 | NR5A2 (0.30) | — | |
| SCHEMBL17791350 | 0.88 | GAA (0.34) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL16803235 | 0.87 | GAA (0.34) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL12345496 | 0.87 | GAA (0.32) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL13677623 | 0.87 | GAA (0.32) | GAAXBP1ATMNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120326084-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-27 | — | — | US | disclosed |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| US-8114310-B2 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20120001123-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA COMPRISING SAME | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-01-05 | — | — | US | disclosed |
| US-8043671-B2 | Liquid-crystalline medium and liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-10-25 | — | — | US | disclosed |
| US-8025935-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2011-09-27 | — | — | US | disclosed |
| US-8017200-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2011-09-13 | — | — | US | disclosed |
| US-20110140039-A1 | Liquid-crystalline medium | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2011-06-16 | — | — | US | disclosed |
| US-7922934-B2 | s-Indacene and indeno[5,6-d][1,3]dioxol-derivatives and use thereof as components of liquid-crystal mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-04-12 | — | — | US | disclosed |
| US-7854970-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-12-21 | — | — | US | disclosed |
| US-7670655-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2010-03-02 | — | — | US | disclosed |
| US-20090324853-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| US-7582337-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2009-09-01 | — | — | US | disclosed |
| US-20080197319-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-7390538-B2 | Liquid-crystal medium containing monofluoroterphenyl compounds | MERCK PATENT GMBH (DE) | 2008-06-24 | — | — | US | disclosed |
| US-20080121843-A1 | Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices | HECKMEIER MICHAEL | 2008-05-29 | — | — | US | disclosed |
| US-20080083902-A1 | an 1-alkoxy-2,3-difluoro-4-cyclohexylenyl-benzene, and a 4,4'(alkyl, alkenyl or alkoxy) bicyclohexyl or a (4 or 4')-(alkyl, alkenyl or alkoxy)phenyl cyclohexane; high specific resistance, short response times, low threshold voltage; for electro-optical liquid-crystal dispaly | MERCK PATENT GMBH | 2008-04-10 | — | — | US | disclosed |
| US-7294368-B2 | Liquid crystal composition for use in bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-11-13 | — | — | US | disclosed |
| US-20070176144-A1 | Liquid crystal composition for bistable liquid crystal devices | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-7250198-B2 | For electrooptical display | MERCK PATENT GMBH (DE) | 2007-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120326084-A1 | LIQUID-CRYSTALLINE MEDIUM | NEFM, VIM, PLG | GAA 2524/4885XBP1 4714/4885ATM 210/4885 |
| US-20080083902-A1 | an 1-alkoxy-2,3-difluoro-4-cyclohexylenyl-benzene, and a 4,4'(alkyl, alkenyl or alkoxy) bicyclohexyl or a (4 or 4')-(alkyl, alkenyl or alkoxy)phenyl cyclohexane; high specific resistance, short response times, low threshold voltage; for electro-optical liquid-crystal dispaly | TRPC4, TRPV4, CACNB4 | GAA 4562/4885XBP1 2687/4885ATM 3062/4885 |
| US-20120001123-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA COMPRISING SAME | TEC, TPMT, TST | GAA 4149/4885XBP1 3443/4885ATM 920/4885 |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | CUTA, NEFM, FES | GAA 4658/4885XBP1 3509/4885ATM 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.