Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ODC1 | P11926 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730711 | 0.96 | CYP3A4 (0.43) | CYP3A4TDP1HTTODC1 | |
| SCHEMBL9349437 | 0.92 | CYP3A4 (0.43) | CYP3A4TDP1HTTODC1 | |
| SCHEMBL6747243 | 0.92 | CYP3A4 (0.43) | CYP3A4TDP1HTTODC1 | |
| SCHEMBL628731 | 0.88 | CYP3A4 (0.46) | CYP3A4TDP1HTTODC1 | |
| SCHEMBL26006878 | 0.87 | CYP3A4 (0.36) | CYP3A4TDP1HTT | |
| SCHEMBL9580780 | 0.84 | CYP3A4 (0.36) | CYP3A4TDP1 | |
| SCHEMBL12119295 | 0.84 | TDP1 (0.41) | TDP1 | |
| SCHEMBL19131302 | 0.84 | TDP1 (0.41) | TDP1 | |
| SCHEMBL12677501 | 0.80 | CYP3A4 (0.43) | CYP3A4ODC1 | |
| SCHEMBL14515641 | 0.80 | CYP1A2 (0.37) | CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377464-B2 | Polymerizable surfactants and their use as device forming comonomers | BAUSCH & LOMB INCORPORATED (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120157565-A1 | Polymerizable Surfactants and Their Use as Device Forming Comonomers | BAUSCH HEALTH US, LLC | 2012-06-21 | — | — | US | disclosed |