Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ODC1 | P11926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971678 | 0.96 | CYP3A4 (0.41) | CYP3A4TDP1HTTODC1 | |
| SCHEMBL628731 | 0.91 | CYP3A4 (0.46) | CYP3A4TDP1HTTODC1 | |
| SCHEMBL26006878 | 0.90 | CYP3A4 (0.36) | CYP3A4TDP1HTT | |
| SCHEMBL6747243 | 0.88 | CYP3A4 (0.43) | CYP3A4TDP1HTTODC1 | |
| SCHEMBL9349437 | 0.88 | CYP3A4 (0.43) | CYP3A4TDP1HTTODC1 | |
| SCHEMBL19131302 | 0.87 | TDP1 (0.41) | TDP1 | |
| SCHEMBL12119295 | 0.87 | TDP1 (0.41) | TDP1 | |
| SCHEMBL12677501 | 0.83 | CYP3A4 (0.43) | CYP3A4ODC1 | |
| SCHEMBL14515641 | 0.83 | CYP1A2 (0.37) | CYP3A4TDP1 | |
| SCHEMBL3029362 | 0.81 | HTT (0.51) | CYP3A4TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702500-B2 | Biomedical devices | BAUSCH + LOMB IRELAND LIMITED (IE) | 2023-07-18 | — | — | US | disclosed |
| US-8389597-B2 | High water content ophthalmic devices | BAUSCH & LOMB INCORPORATED (US) | 2013-03-05 | — | — | US | disclosed |
| US-8197841-B2 | Polymerizable surfactants and their use as device forming comonomers | BAUSCH & LOMB INCORPORATED (US) | 2012-06-12 | — | — | US | disclosed |
| US-20120141408-A1 | High Water Content Ophthalmic Devices | SOLTA MEDICAL, INC. | 2012-06-07 | — | — | US | disclosed |
| US-8138290-B2 | High water content ophthalmic devices | BAUSCH & LOMB INCORPORATED (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090191256-A1 | HIGH WATER CONTENT OPHTHALMIC DEVICES | BAUSCH HEALTH AMERICAS, INC. | 2009-07-30 | — | — | US | disclosed |
| US-20090145091-A1 | METHOD FOR TREATING OPHTHALMIC LENSES | CONNOLLY RICHARD | 2009-06-11 | — | — | US | disclosed |
| US-20090145086-A1 | METHOD FOR TREATING OPHTHALMIC LENSES | REYNOLDS GER M | 2009-06-11 | — | — | US | disclosed |
| US-20090142292-A1 | Method For The Mitigation of Symptoms of Dry Eye | BAUSCH & LOMB INCORPORATED | 2009-06-04 | — | — | US | disclosed |
| US-20090142387-A1 | Method For Inhibiting Attachment Of Microorganisms To Biomedical Devices | BAUSCH & LOMB INCORPORATED | 2009-06-04 | — | — | US | disclosed |
| US-20070122540-A1 | Coatings on ophthalmic lenses | BAUSCH & LOMB INCORPORATED | 2007-05-31 | — | — | US | disclosed |
| US-20070120279-A1 | Method for coating lens material | BAUSCH & LOMB INCORPORATED | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120141408-A1 | High Water Content Ophthalmic Devices | AQP1, AQP3, AQP4 | CYP3A4 4616/4885TDP1 2592/4885HTT 1788/4885 |
| US-20090142387-A1 | Method For Inhibiting Attachment Of Microorganisms To Biomedical Devices | MIF, MSN, NAPA | CYP3A4 2055/4885TDP1 3668/4885HTT 3974/4885 |
| US-20090142292-A1 | Method For The Mitigation of Symptoms of Dry Eye | CSTB, CFB, MSN | CYP3A4 2305/4885TDP1 3506/4885HTT 3366/4885 |
| US-20090191256-A1 | HIGH WATER CONTENT OPHTHALMIC DEVICES | AQP1, AQP3, AQP4 | CYP3A4 4616/4885TDP1 2592/4885HTT 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.