SCHEMBL9972490

SCHEMBL9972490

CC(C)(C)c1ccc(C(=O)N(CC(=O)O)CC(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 8/20 0.54
SRD5A2 P31213 1/20 0.50
EPHX2 P34913 4/20 0.48
HDAC1 Q13547 1/20 0.47
ESRRG P62508 1/20 0.47
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
RARB P10826 1/20 0.46
RARG P13631 1/20 0.46
MLYCD O95822 1/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31035984 0.86 NR1H4 (0.46) NR1H4SRD5A2EPHX2HDAC1ESRRG
SCHEMBL31035930 0.86 NR1H4 (0.46) NR1H4SRD5A2EPHX2HDAC1ESRRG
SCHEMBL11515014 0.81 MLYCD (0.61) NR1H4EPHX2HDAC1ESRRGRAB9A
SCHEMBL6284193 0.79 ESRRG (0.50) NR1H4SRD5A2EPHX2HDAC1ESRRG
SCHEMBL2226134 0.77 HPGD (0.55) HDAC1MAPTSMN1; SMN2
SCHEMBL30491048 0.76 MLYCD (0.54) NR1H4SRD5A2EPHX2HDAC1ESRRG
SCHEMBL12443251 0.76 EGFR (0.57) NR1H4EPHX2HDAC1ESRRGMAPT
SCHEMBL4403418 0.75 NR1H4 (0.68) NR1H4SRD5A2EPHX2HDAC1ESRRG
SCHEMBL28361320 0.75 ESRRG (0.54) NR1H4SRD5A2EPHX2HDAC1ESRRG
SCHEMBL13227108 0.75 ESRRG (0.50) NR1H4EPHX2ESRRGMAPTMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394309-B2 Resin film and method for producing it, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-03-12 US disclosed
US-8394309-B2 Resin film and method for producing it, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-03-12 US disclosed
US-20120153542-A1 RESIN FILM AND METHOD FOR PRODUCING IT, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153542-A1 RESIN FILM AND METHOD FOR PRODUCING IT, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed