Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12125156 | 0.85 | MEN1 (0.44) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8771837 | 0.84 | MAPK14 (0.41) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL15214810 | 0.84 | PTPN1 (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9973051 | 0.84 | KMT2A (0.38) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9973043 | 0.82 | NPC1 (0.46) | MEN1KMT2AALDH1A1MCHR1TP53 | |
| SCHEMBL9973153 | 0.79 | HDAC3 (0.48) | LMNAKMT2AALDH1A1MAPTMAPK14 | |
| SCHEMBL9973104 | 0.78 | HDAC3 (0.51) | MEN1KMT2AALDH1A1MCHR1TP53 | |
| SCHEMBL9973102 | 0.76 | KMT2A (0.48) | MEN1KMT2AALDH1A1MAPK14ABL1 | |
| SCHEMBL12127084 | 0.76 | MAPT (0.38) | MEN1KMT2AMAPTNPSR1NPC1 | |
| SCHEMBL9973053 | 0.72 | MAPT (0.40) | MEN1KMT2AMAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082383-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20110279883-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110143141-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110143141-A1 | Photochromic compounds and compositions | CCNA1, CRY1, CCNT1 | LMNA 230/4885SMN1; SMN2 3964/4885MEN1 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.