⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12047732 | 1.00 | — | — | |
| SCHEMBL10301851 | 1.00 | — | — | |
| SCHEMBL10301506 | 0.78 | — | — | |
| SCHEMBL9971819 | 0.78 | — | — | |
| SCHEMBL10301505 | 0.78 | — | — | |
| SCHEMBL13241916 | 0.78 | — | — | |
| SCHEMBL5983221 | 0.78 | GABRP (0.37) | — | |
| SCHEMBL9971808 | 0.78 | — | — | |
| SCHEMBL13241917 | 0.78 | — | — | |
| SCHEMBL23925610 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768804-B1 | 2-METHYLENE-VITAMIN D ANALOGS AND THEIR USES | WISCONSIN ALUMNI RES FOUND (US) | 2018-02-28 | — | — | EP | disclosed |
| EP-2721004-B1 | 3-DESOXY-2-METHYLENE-19-NOR-VITAMIN D ANALOGS AND THEIR USES | WISCONSIN ALUMNI RES FOUND (US) | 2017-07-26 | — | — | EP | disclosed |
| US-8993547-B2 | 3-desoxy-2-methylene-19-nor-vitamin D analogs and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-03-31 | — | — | US | disclosed |
| US-8785422-B2 | A-ring modified 19-nor-vitamin D analogs and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-22 | — | — | US | disclosed |
| US-8729054-B2 | 3-desoxy-2-methylene-vitamin D analogs and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-05-20 | — | — | US | disclosed |
| US-8642579-B2 | 1-desoxy-2-methylene-19-nor-vitamin D analogs and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-02-04 | — | — | US | disclosed |
| US-8518917-B2 | 2-methylene-19-nor-vitamin D analogs and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-08-27 | — | — | US | disclosed |
| US-8455467-B2 | 2-methylene-vitamin D analogs and their uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-06-04 | — | — | US | disclosed |
| US-20130102567-A1 | 3-Desoxy-2-Methylene-Vitamin D Analogs and Their Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102573-A1 | 2-METHYLENE-VITAMIN D ANALOGS AND THEIR USES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-04-25 | — | — | US | disclosed |
| US-20100009945-A1 | 19-NOR-VITAMIN D ANALOGS WITH 3,2-DIHYDROFURAN RING | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-01-14 | — | — | US | disclosed |
| US-7598408-B2 | Intermediates for synthesis of vitamin D derivatives | KNC LABORATORIES CO., LTD. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-20090143342-A1 | 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION OF MADISON | 2009-06-04 | — | — | US | disclosed |
| WO-2009026265-A1 | A METHOD OF EXTENDING THE DOSE RANGE OF VITAMIN D COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-02-26 | — | — | WO | disclosed |
| US-7468361-B2 | 2-ethyl and 2-ethylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-12-23 | — | — | US | disclosed |
| US-20080032956-A1 | 2-Ethyl and 2-Ethylidene-19-Nor-Vitamin D Compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-02-07 | — | — | US | disclosed |
| US-7300925-B2 | 2-ethyl and 2-ethylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-11-27 | — | — | US | disclosed |
| US-7259143-B2 | Method of extending the dose range of vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-08-21 | — | — | US | disclosed |
| US-7241747-B2 | 2-propylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-20070088008-A1 | 2-Ethyl and 2-ethylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-04-19 | — | — | US | disclosed |