SCHEMBL9973587

SCHEMBL9973587

O=C1c2cc(F)c(F)cc2C(=O)c2cc(F)c(F)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.39
ESR1 P03372 1/20 0.39
MAOA P21397 1/20 0.39
UGT1A1 P22309 1/20 0.39
ESR2 Q92731 1/20 0.39
PTPRC P08575 1/20 0.38
PTPN1 P18031 1/20 0.38
BCL2 P10415 1/20 0.38
MCL1 Q07820 1/20 0.38
MEN1 O00255 1/20 0.37
CDC25B P30305 1/20 0.37
KMT2A Q03164 1/20 0.37
PTGS2 P35354 5/20 0.37
PTGS1 P23219 2/20 0.37
TGM2 P21980 1/20 0.36
ELANE P08246 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10607728 0.86 MEN1 (0.63) MAOBMAOAPTPRCPTPN1BCL2
SCHEMBL650112 0.84 MAOB (0.35) MAOBESR1MAOAUGT1A1ESR2
SCHEMBL24253313 0.82 PTPRC (0.33) PTPRCPTPN1PTGS2PTGS1TGM2
SCHEMBL9240891 0.82 MEN1 (0.43) MAOBPTPRCPTPN1BCL2MCL1
SCHEMBL9736763 0.78 PTPRC (0.44) MAOBPTPRCPTPN1BCL2MCL1
SCHEMBL30886640 0.76 PTPRC (0.62) MAOAPTPRCPTPN1BCL2MCL1
SCHEMBL650601 0.74 MEN1 (0.42) MAOBPTPRCPTPN1BCL2MCL1
SCHEMBL1081926 0.73 GRM5 (0.55) MAOBMAOAMEN1KMT2ATGM2
SCHEMBL9781086 0.72 MEN1 (0.42) MAOBESR1MAOAUGT1A1ESR2
SCHEMBL29441718 0.71 ALOX15 (0.48) PTPRCPTPN1MCL1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823375-A Green solid-phase synthesis method of polyarylether covalent organic framework material 南开大学 2025-04-15 CN claimed
CN-108855012-B Polyarylether covalent organic framework material and preparation method thereof 吉林大学 2020-10-13 CN claimed
CN-108855012-A A kind of polyarylether class covalent organic framework material and preparation method thereof 吉林大学 2018-11-23 CN claimed
CN-119823375-A Green solid-phase synthesis method of polyarylether covalent organic framework material 南开大学 2025-04-15 CN disclosed
CN-108855012-B Polyarylether covalent organic framework material and preparation method thereof 吉林大学 2020-10-13 CN disclosed
US-9522364-B2 Treated mixed matrix polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-20 US disclosed
US-9522364-B2 Treated mixed matrix polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-20 US disclosed
US-9492785-B2 UV and thermally treated polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-15 US disclosed
US-9492785-B2 UV and thermally treated polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-15 US disclosed
US-20160263531-A1 PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263531-A1 PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20100304112-A1 MICROPOROUS POLYMER MATERIAL THE UNIVERSITY OF MANCHESTER (GB) 2010-12-02 US disclosed
US-20100304112-A1 MICROPOROUS POLYMER MATERIAL THE UNIVERSITY OF MANCHESTER (GB) 2010-12-02 US disclosed
US-7758751-B1 UV-cross-linked membranes from polymers of intrinsic microporosity for liquid separations UOP LLC (US) 2010-07-20 US disclosed
US-7690514-B2 Microporous polymer material THE UNIVERSITY OF MANCHESTER (GB) 2010-04-06 US disclosed
US-7690514-B2 Microporous polymer material THE UNIVERSITY OF MANCHESTER (GB) 2010-04-06 US disclosed
US-20080295691-A1 UV CROSS-LINKED POLYMER FUNCTIONALIZED MOLECULAR SIEVE/POLYMER MIXED MATRIX MEMBRANES UOP LLC 2008-12-04 US disclosed
US-20080295692-A1 UV CROSS-LINKED POLYMER FUNCTIONALIZED MOLECULAR SIEVE/POLYMER MIXED MATRIX MEMBRANES FOR SULFUR REDUCTION UOP LLC 2008-12-04 US disclosed
US-20080296527-A1 UV CROSS-LINKED POLYMER FUNCTIONALIZED MOLECULAR SIEVE/POLYMER MIXED MATRIX MEMBRANES UOP LLC 2008-12-04 US disclosed
US-20080300336-A1 UV CROSS-LINKED POLYMER FUNCTIONALIZED MOLECULAR SIEVE/POLYMER MIXED MATRIX MEMBRANES UOP LLC 2008-12-04 US disclosed