Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973883 | 0.86 | MAOB (0.52) | PAMHTR2AMAOBGLATDP1 | |
| SCHEMBL5611191 | 0.79 | PAM (0.53) | PAMHTR2AIDO1MAOBALDH1A1 | |
| SCHEMBL5611194 | 0.79 | PAM (0.53) | PAMHTR2AIDO1MAOBALDH1A1 | |
| SCHEMBL18486435 | 0.79 | MEN1 (0.47) | PAMHTR2AIDO1MEN1KMT2A | |
| SCHEMBL18486434 | 0.79 | MEN1 (0.47) | PAMHTR2AIDO1MEN1KMT2A | |
| SCHEMBL13534799 | 0.78 | GRIN2D (0.34) | PAMNFE2L2ALOX5 | |
| SCHEMBL28995211 | 0.78 | PAM (0.52) | PAMHTR2AIDO1MAOBALDH1A1 | |
| SCHEMBL28158015 | 0.78 | PAM (0.47) | PAMHTR2AIDO1MEN1KMT2A | |
| SCHEMBL28995212 | 0.78 | PAM (0.52) | PAMHTR2AIDO1MAOBALDH1A1 | |
| SCHEMBL27831824 | 0.76 | PAM (0.50) | PAMHTR2AIDO1MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403854-B2 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-08-02 | — | — | US | disclosed |
| US-20140288319-A1 | CROSS-METATHESIS REACTION OF FUNCTIONALIZED AND SUBSTITUTED OLEFINS USING GROUP 8 TRANSITION METAL CARBENE COMPLEXES AS METATHESIS CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-25 | — | — | US | disclosed |
| US-8546049-B2 | Electrophotographic photoconductor and image forming apparatus using the same | SHARP KABUSHIKI KAISHA (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20120156600-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS USING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20110104600-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS USING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288319-A1 | CROSS-METATHESIS REACTION OF FUNCTIONALIZED AND SUBSTITUTED OLEFINS USING GROUP 8 TRANSITION METAL CARBENE COMPLEXES AS METATHESIS CATALYSTS | OXER1, OSTC, OXSR1 | PAM 907/4885HTR2A 4167/4885IDO1 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.