Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048566 | 0.78 | GAA (0.50) | GAASMN1; SMN2ALOX15DRD4 | |
| SCHEMBL17045671 | 0.75 | SMN1; SMN2 (0.51) | GAASMN1; SMN2ALOX15DRD4 | |
| SCHEMBL1695005 | 0.74 | GAA (0.54) | GAASMN1; SMN2ALOX15DRD4MAPK1 | |
| SCHEMBL2685502 | 0.73 | KDR (0.53) | GAASMN1; SMN2KDRMAPK14MAPK1 | |
| SCHEMBL13135667 | 0.71 | DRD2 (0.52) | GAASMN1; SMN2DRD4 | |
| SCHEMBL22633243 | 0.71 | HPGD (0.57) | GAASMN1; SMN2ALOX15 | |
| SCHEMBL25793180 | 0.71 | GAA (0.50) | GAASMN1; SMN2ALOX15MAPK14 | |
| SCHEMBL14335096 | 0.69 | GAA (1.00) | GAASMN1; SMN2ALOX15MAPK14DRD4 | |
| SCHEMBL17619510 | 0.69 | SMN1; SMN2 (0.43) | GAASMN1; SMN2MAPK1 | |
| SCHEMBL14500140 | 0.68 | DPP4 (0.49) | GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9192697-B2 | Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis | HEMOTEQ AG (DE) | 2015-11-24 | — | — | US | disclosed |
| US-8597720-B2 | Medical product for treating stenosis of body passages and for preventing threatening restenosis | HEMOTEQ AG (DE) | 2013-12-03 | — | — | US | disclosed |
| US-20110287169-A1 | MEDICAL PRODUCT FOR TREATING STENOSIS OF BODY PASSAGES AND FOR PREVENTING THREATENING RESTENOSIS | HEMOTEQ AG | 2011-11-24 | — | — | US | disclosed |
| US-20110160698-A1 | Balloon Catheter for Treating Stenosis of Body Passages and for Preventing Threatening Restenosis | HEMOTEQ AG (DE) | 2011-06-30 | — | — | US | disclosed |
| EP-2269664-A2 | Medical product for treating closures of bodily passages and preventing reclosures | Hemoteq AG (DE) | 2011-01-05 | — | — | EP | disclosed |
| US-20100179475-A1 | MEDICAL PRODUCT FOR TREATING STENOSIS OF BODY PASSAGES AND FOR PREVENTING THREATENING RESTENOSIS | HEMOTEQ AG (DE) | 2010-07-15 | — | — | US | disclosed |
| EP-2136853-A2 | MEDICAL PRODUCT FOR TREATING STENOSIS OF BODY PASSAGES AND FOR PREVENTING THREATENING RESTENOSIS | Hemoteq AG (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008086794-A2 | MEDICAL PRODUCT FOR TREATING STENOSIS OF BODY PASSAGES AND FOR PREVENTING THREATENING RESTENOSIS | HEMOTEQ AG (DE) | 2008-07-24 | — | — | WO | disclosed |