Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9974149 | 0.84 | GPR119 (0.51) | GPR119CLK2CLK3GSK3BDYRK1A | |
| SCHEMBL9942277 | 0.83 | GPR119 (0.58) | GPR119 | |
| SCHEMBL9974215 | 0.83 | GPR119 (0.53) | GPR119CLK2CLK3GSK3BDYRK1A | |
| SCHEMBL9940530 | 0.83 | GPR119 (0.58) | GPR119PIK3CAMTOR | |
| SCHEMBL9974188 | 0.82 | GPR119 (0.54) | GPR119PIK3CAMTOR | |
| SCHEMBL9937978 | 0.82 | GPR119 (0.56) | GPR119PIK3CAMTORCLK2CLK3 | |
| SCHEMBL9974206 | 0.81 | GPR119 (0.60) | GPR119 | |
| SCHEMBL9943188 | 0.80 | GPR119 (0.53) | GPR119 | |
| SCHEMBL9943221 | 0.80 | GPR119 (0.62) | GPR119 | |
| SCHEMBL9937417 | 0.80 | GPR119 (0.59) | GPR119PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080476-A1 | FUSED DIHYDROPYRANS AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY AND RELATED DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |