SCHEMBL997454

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL996771	0.80	FEN1 (0.41)	ALDH1A1L3MBTL1MAPTHSD17B10RAB9A
	SCHEMBL996294	0.77	TSHR (0.44)	CYP3A4SMN1; SMN2ALDH1A1L3MBTL1MAPT
	SCHEMBL10141022	0.75	CYP11B1 (0.48)	TDP1TP53SMN1; SMN2CYP11B1CYP11B2
	SCHEMBL11698155	0.74	CDC7 (0.59)	TP53SMN1; SMN2ALDH1A1MAPTHSD17B10
	SCHEMBL11698160	0.73	SMN1; SMN2 (0.48)	TDP1THRBALOX15CYP3A4TP53
	SCHEMBL16735817	0.73	GSK3B (0.41)	ALOX15SMN1; SMN2ALDH1A1HSD17B10POLB
	SCHEMBL2093617	0.72	L3MBTL1 (0.41)	TP53SMN1; SMN2CYP11B1CYP11B2ALDH1A1
	SCHEMBL26759056	0.70	HDAC1 (0.41)	TP53SMN1; SMN2CYP11B1CYP11B2ALDH1A1
	SCHEMBL996557	0.70	SREBF2 (0.43)	TDP1THRBALOX15CYP3A4TP53
	SCHEMBL18015904	0.69	MAPT (0.39)	TDP1ALOX15ALDH1A1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.