Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CCR9 | P51686 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20951622 | 0.81 | QRFPR (0.44) | CNR2CCR9KDM4ESMN1; SMN2CRHBP | |
| SCHEMBL30617317 | 0.81 | QRFPR (0.44) | CNR2CCR9KDM4ESMN1; SMN2CRHBP | |
| SCHEMBL16235855 | 0.79 | CCR9 (0.39) | CCR9KDM4ESMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL16254720 | 0.78 | CCR9 (0.39) | CCR9KDM4ESMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL17556112 | 0.78 | CCR9 (0.39) | CCR9KDM4ESMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL2815834 | 0.76 | NOD2 (0.51) | CCR9KDM4ESMN1; SMN2NOD2NOD1 | |
| Hydrochloric Acid SCHEMBL28848977 | 0.73 | KDM4E (0.45) | CNR2KDM4ESMN1; SMN2CRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL30104789 | 0.72 | KDM4E (0.43) | KDM4ESMN1; SMN2CRHBPCRHR2NOD2 | |
| SCHEMBL24187332 | 0.72 | KDM4E (0.44) | KDM4ESMN1; SMN2CRHBPCRHR2NOD2 | |
| SCHEMBL7911379 | 0.72 | CCR9 (0.43) | CCR9KDM4ESMN1; SMN2NOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160251377-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-09-01 | — | — | US | claimed |
| US-9896459-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-20 | — | — | US | disclosed |
| US-9896459-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-20 | — | — | US | disclosed |
| EP-2651936-B1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-02-22 | — | — | EP | disclosed |
| US-20160251377-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-09-01 | — | — | US | disclosed |
| US-20160251377-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-09-01 | — | — | US | disclosed |
| US-9339494-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IR) | 2016-05-17 | — | — | US | disclosed |
| US-9339494-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IR) | 2016-05-17 | — | — | US | disclosed |
| US-20150231119-A1 | Azaindoles As Respiratory Syncytial Virus Antiviral Agents | JANSSEN SCIENCES IRELAND UC (IE) | 2015-08-20 | — | — | US | disclosed |
| US-20150231119-A1 | Azaindoles As Respiratory Syncytial Virus Antiviral Agents | JANSSEN SCIENCES IRELAND UC (IE) | 2015-08-20 | — | — | US | disclosed |
| US-9051317-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2015-06-09 | — | — | US | disclosed |
| US-9051317-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2015-06-09 | — | — | US | disclosed |
| US-20130267556-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2013-10-10 | — | — | US | disclosed |
| US-20130267556-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2013-10-10 | — | — | US | disclosed |
| WO-2012080450-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150231119-A1 | Azaindoles As Respiratory Syncytial Virus Antiviral Agents | AZI2, CCNI, ZC3HAV1 | CNR2 4714/4885CCR9 3295/4885KDM4E 1448/4885 |
| US-20160251377-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | AZI2, CCNI, ZC3HAV1 | CNR2 4714/4885CCR9 3295/4885KDM4E 1448/4885 |
| US-20130267556-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | AZI2, CCNI, ZC3HAV1 | CNR2 4714/4885CCR9 3295/4885KDM4E 1448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.