SCHEMBL9974660

SCHEMBL9974660

COC/C=C(\C#N)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.41
ADORA2A P29274 1/20 0.39
ADORA2B P29275 1/20 0.39
ADORA1 P30542 1/20 0.39
POLB P06746 1/20 0.37
APP P05067 2/20 0.36
KDM4E B2RXH2 5/20 0.35
ALDH1A1 P00352 5/20 0.35
KMT2A Q03164 4/20 0.35
LMNA P02545 4/20 0.35
MAPT P10636 3/20 0.35
TNNI3 P19429 1/20 0.35
CRHBP P24387 1/20 0.35
TNNT2 P45379 1/20 0.35
KLK7 P49862 1/20 0.35
TNNC1 P63316 1/20 0.35
CRHR2 Q13324 1/20 0.35
SNCA P37840 1/20 0.35
MEN1 O00255 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13750059 0.83 CYP2C9 (0.45) CYP2C9ADORA2AADORA2BADORA1POLB
SCHEMBL2671871 0.82 CYP2C9 (0.42) CYP2C9ADORA2AADORA2BADORA1POLB
SCHEMBL10167752 0.82 CYP2C9 (0.42) CYP2C9ADORA2AADORA2BADORA1POLB
SCHEMBL10136090 0.82 ADORA2A (0.40) CYP2C9ADORA2AADORA2BADORA1POLB
SCHEMBL4072774 0.82 ADORA2A (0.40) CYP2C9ADORA2AADORA2BADORA1POLB
SCHEMBL15309080 0.82 KDM4E (0.40) CYP2C9KDM4EALDH1A1KMT2ALMNA
SCHEMBL27679283 0.78 CYP2C9 (0.40) CYP2C9ADORA2AADORA2BADORA1POLB
SCHEMBL17859724 0.78 CYP2C9 (0.40) CYP2C9ADORA2AADORA2BADORA1POLB
SCHEMBL18655709 0.78
SCHEMBL7618854 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120156449-A1 INK SET, RECORDING METHOD, RECORDED MATERIAL AND PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed